EEG Monitoring for PERFormance Anticipation

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Other: Electroencephalography (EEG) multi-sensor; Other: Magnetoencephalography (MEG); Other: Behavioral Measures; Other: Reaction time measurement; Other: Assessment of physical performance; Other: Electrooculogram (EOG); Other: Electromyogram (EMG); Other: Electrocardiogram with 3 leads; Other: Electrodermogram (EDG); Other: Consumption of O2 (VO2); Other: Production of CO2 (VCO2)

• Registration Number: NCT03233282
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Identify, characterize and then validate electrophysiological markers linking electrophysiological cerebral activity and performance in cognitive and physical fatigability in humans. To do this, noninvasive explorations of electroencephalography (EEG) and magnetoencephalography (MEG) will be carried out under two conditions of different experiments, the first one that induces a cognitive fatigability and the second one that induces physical fatigability.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-05-30
• Study First Submitted: 2017-04-25
• Study First Submitted QC: 2017-07-25
• Study First Posted: 2017-07-28
• Primary Completion: 2018-05-31
• Study Completion: 2018-05-31
• Status Verified: 2018-08
• Last Update Submitted: 2018-08-30
• Last Update Posted: 2018-08-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 169

Inclusion Criteria

Not provided

Read More

Exclusion Criteria

• Pregnant women, nursing mothers or those of childbearing age without contraception
• Persons under guardianship, curatorship or any other administrative or judicial measure of deprivation of liberty or of liberty
• Persons protected by the law
• Persons who have performed a maximum stress test within 15 days of the date of inclusion,
• In the course of drug treatments against indicated for the protocol (treatment for neurological diseases, psychiatric ...).
• Metal implants incompatible with MRI (for the subjects concerned, see appendices)
• Metallic implants incompatible with the MEG (for the subjects concerned, see appendices)

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Physical Fatigability	Behavioral Measures	-
Cognitive Fatigability	Magnetoencephalography (MEG)	-
Cognitive Fatigability	Electrooculogram (EOG)	-
Physical Fatigability	Assessment of physical performance	-
Physical Fatigability	Production of CO2 (VCO2)	-
Physical Fatigability	Electroencephalography (EEG) multi-sensor	-
Cognitive Fatigability	Electroencephalography (EEG) multi-sensor	-
Cognitive Fatigability	Electrocardiogram with 3 leads	-
Physical Fatigability	Reaction time measurement	-
Physical Fatigability	Magnetoencephalography (MEG)	-
Cognitive Fatigability	Behavioral Measures	-
Cognitive Fatigability	Reaction time measurement	-
Cognitive Fatigability	Assessment of physical performance	-
Cognitive Fatigability	Electromyogram (EMG)	-
Physical Fatigability	Electrooculogram (EOG)	-
Physical Fatigability	Electrodermogram (EDG)	-
Physical Fatigability	Electrocardiogram with 3 leads	-
Physical Fatigability	Electromyogram (EMG)	-
Physical Fatigability	Consumption of O2 (VO2)	-

Primary Outcome Measures

Name	Time	Method
Identify electrophysiological markers in humans depending on whether the experimental conditions induce cognitive fatigability.	7 hours	The evaluation of cognitive performance will be carried out by means of conventional behavioral measures, of the press-button type, handling of a mouse or of a joystick and measurement of reaction time.
Identify electrophysiological markers in humans depending on whether the experimental conditions induce physical fatigability with EEG.	7 hours	Electrophysiological measurements of cerebral activity will be performed by multi-sensor electroencephalography (EEG).
Identify electrophysiological markers in humans depending on whether the experimental conditions induce physical fatigability with MEG.	7 hours	Electrophysiological measurements of cerebral activity will be carried out by magnetoencephalography (MEG)

Secondary Outcome Measures

Name	Time	Method
Refine (locate at the level of the cortex), the origin of these physiological markers	7 hours	Several types of recordings, passive and non-invasive, will be realized: * Electrooculogram (EOG); * electromyography (EMG); * electrocardiogram (ECG); Systematically in "physical" experiments and for some "cognitive" experiments.
Distinguish between different time scales of performance	7 hours	Several types of recordings, passive and non-invasive, will be realized: * electrodermogram (EDG); * the consumption of O2 (VO2); * production of CO2 (VCO2). Only and systematically, in "physical" experiments.

Trial Locations

Locations (1)

Hospices Civils de Lyon, HFME; 🇫🇷 Bron, France