Electrophysiological and Bioenergetic Study of Variations in Cognitive and Physical Performance in Healthy Humans: EEG Monitoring for PERFormance Anticipation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Healthy
- Sponsor
- Hospices Civils de Lyon
- Enrollment
- 169
- Locations
- 1
- Primary Endpoint
- Identify electrophysiological markers in humans depending on whether the experimental conditions induce cognitive fatigability.
- Status
- Completed
- Last Updated
- 7 months ago
Overview
Brief Summary
Identify, characterize and then validate electrophysiological markers linking electrophysiological cerebral activity and performance in cognitive and physical fatigability in humans. To do this, noninvasive explorations of electroencephalography (EEG) and magnetoencephalography (MEG) will be carried out under two conditions of different experiments, the first one that induces a cognitive fatigability and the second one that induces physical fatigability.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •Pregnant women, nursing mothers or those of childbearing age without contraception
- •Persons under guardianship, curatorship or any other administrative or judicial measure of deprivation of liberty or of liberty
- •Persons protected by the law
- •Persons who have performed a maximum stress test within 15 days of the date of inclusion,
- •In the course of drug treatments against indicated for the protocol (treatment for neurological diseases, psychiatric ...).
- •Metal implants incompatible with MRI (for the subjects concerned, see appendices)
- •Metallic implants incompatible with the MEG (for the subjects concerned, see appendices)
Outcomes
Primary Outcomes
Identify electrophysiological markers in humans depending on whether the experimental conditions induce cognitive fatigability.
Time Frame: 7 hours
The evaluation of cognitive performance will be carried out by means of conventional behavioral measures, of the press-button type, handling of a mouse or of a joystick and measurement of reaction time.
Identify electrophysiological markers in humans depending on whether the experimental conditions induce physical fatigability with EEG.
Time Frame: 7 hours
Electrophysiological measurements of cerebral activity will be performed by multi-sensor electroencephalography (EEG).
Identify electrophysiological markers in humans depending on whether the experimental conditions induce physical fatigability with MEG.
Time Frame: 7 hours
Electrophysiological measurements of cerebral activity will be carried out by magnetoencephalography (MEG)
Secondary Outcomes
- Refine (locate at the level of the cortex), the origin of these physiological markers(7 hours)
- Distinguish between different time scales of performance(7 hours)