euroMuscleAssociation between acute muscle wasting and functional deficits following severe traumatic brain injury: observational cohort study

Not Applicable

• Conditions: Traumatic brain injury; Acute muscle loss (Secondary sarcopenia); Functional deficits; Catabolic state; Intracerebral haemorrhage; Epidural haemorrhage; Subarachnoid haemorrhage; Subdural haemorrhage; Diffuse axonal injury; Intraparenchymal Haemorrhage

• Registration Number: ACTRN12621001196831
• Lead Sponsor: Metro South Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-09-08
• Last Update Posted: 13 September 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Able to have a family member or next of kin consent on the patient’s behalf.
2. Traumatic brain injury (TBI) requiring an intensive care unit admission.
Injuries may include:
Intracerebral haemorrhage
Epidural haemorrhage
Subdural haemorrhage
Subarachnoid haemorrhage
Intraparenchymal Haemorrhage
Diffuse axonal injury

Exclusion Criteria

1. Dire prognosis (i.e. unlikely to survive the current admission)
2. Spinal cord injury
3. Acute injuries that prohibit ultrasound assessment of thigh musculature i.e. lacerations or open wounds.
4. People who are incarcerated.
5. Women who are pregnant
6. Participants with significant pre-existing cognitive impairment, intellectual disability or mental illness.

Study & Design

• Study Type: Observational
• Study Design: Not specified