Investigation of the Effects of Discontinuing Beta Blockers on Exercise Tolerance in Patients with Chronic Myocardial Infarction and Preserved Left Ventricular Ejection Fractio
- Conditions
- Chronic Myocardial Infarction with Preserved Left Ventricular Ejection Fraction"
- Registration Number
- JPRN-UMIN000052909
- Lead Sponsor
- Juntendo University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 100
Not provided
1. Individuals using implantable medical devices such as cardiac pacemakers or defibrillators. 2. Patients taking beta blockers for tachyarrhythmias. 3. Patients taking digitalis preparations, calcium channel blockers (verapamil, diltiazem), or ivabradine. 4. Patients diagnosed with acute phase of acute myocardial infarction, unstable angina not stable with medical treatment, uncontrolled arrhythmias causing symptoms or hemodynamic abnormalities, uncontrolled heart failure, uncontrolled hypertension, symptomatic severe aortic stenosis, or mental illness that precludes communication. Definition of heart failure symptoms: a) Dyspnea induced at rest or with mild exertion. b) At least two of the following: jugular venous distention, pulmonary rales, peripheral edema, or chest Xray showing pulmonary congestion. 5. Patients deemed unsuitable for the study by the principal investigator or co-investigator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method