Prevention of nausea and vomiting comparing ondansetron and dexamethasone versus placebo in cesarean section under regional anesthesia

Phase 4

Completed

• Conditions: 1. Postoperative nausea and vomiting 2. Pruritus; Signs and Symptoms

• Registration Number: ISRCTN57227250
• Lead Sponsor: Industrial University of Santander (Universidad Industrial de Santander)

Brief Summary

2018 results [in Spanish] in https://revistas.uis.edu.co/index.php/revistamedicasuis/article/view/8190 (added 09/08/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-07-17
• Study Completion: 2016-09-01
• Last Update Posted: 2 September 2019

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 300

Inclusion Criteria

1. Pregnant patients scheduled for elective caesarean
2. Age between 18 - 40 years old
3. Spinal (Subarachnoid) anesthesia with intrathecal morphine
4. ASA Physical status 1-2

Exclusion Criteria

1. Preeclampsia
2. Eclampsia
3. Kidney and/or liver failure
4. Known allergy to ondansetron or dexamethasone
5. Heart disease
6. Vertigo
7. Hyperemesis gravidarum
8. Nausea and vomiting or itching
9. Previous cesarean section
10. 5 HT3 antagonists or corticoids allergy
11. Gestational diabetes
12. Immunosuppression
13. Congenital long QT syndrome
14. Neurological or psychiatric illness that would prevent obtaining consent for the study Emergency Caesarean
.

Study & Design

• Study Type: Interventional
• Study Design: Not specified