Efficacy of the Anterior Quadratus Lumborum Block Versus the Transversus Abdominis Plane Block for Elective Laparoscopic Inguinal Hernia Repair: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Opioid consumption measured as orale morphine equivalents.
研究概览
简要总结
One of the most common complications after hernia repair is postoperative and chronic pain. TAP (transverse abdominis plain) block is a recommended multimodal method of reducing postoperative pain in laparoscopic and open inguinal hernia repair. The objective of this study is to determine whether the use of a perioperative echo guided unilateral TAP block has a superior effect on postoperative pain after laparoscopic inguinal repair compared to an anterior Quadratus Lumborum Block with a long acting local anesthetic.
详细描述
One of the most common complications after hernia repair is postoperative and chronic pain. Postoperative pain is an expected but undesirable effect after an operation, which can result in an prolonged hospital stay or longer time to return fully to normal daily activities. There are indications that an insufficient treatment of postoperative pain is a risk factor for persistent or chronic pain after open and laparoscopic inguinal hernia repair (Berndsen FH 2007) (Nienhuijs SW 2005).
TAP (transverse abdominis plain) block is a recommended multimodal method of reducing postoperative pain in laparoscopic and open surgery (El-Dawlatly AA 2009; 102). TAP block (Meyer A 2015) and an anterior Quadratus Lumborum Block (Adhikary, S.D. 2017) are both recommended for inguinal hernia repair. The objective of this study is to determine, whether the use of a perioperative echo guided unilateral TAP block has a superior effect on postoperative pain after laparoscopic inguinal repair compared to the anterior Quadratus Lumborum Block with a long acting local anesthetic. There will be no further analysis in this study regarding the evidence of open hernia inguinal repair and chronic pain.
The primary endpoint:
Opioid consumption measured in orale morphine equivalents four hours postoperative.
The secondary endpoints:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
盲法说明
Computer generated randomization with allocation in opaque envelopes. Randomization performed by other study personell than care provider.
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Transmuscular Quadratus lumborum Block
A single shot unilateral transmuscular Quadratus lumborum Block with Ropivacaine 7,5 mg/ml, 20 ml
干预措施: Oksykodonhydroklorid (Drug)
Transmuscular Quadratus lumborum Block
A single shot unilateral transmuscular Quadratus lumborum Block with Ropivacaine 7,5 mg/ml, 20 ml
干预措施: Ondansetron and Droperidol (Drug)
Transmuscular Quadratus lumborum Block
A single shot unilateral transmuscular Quadratus lumborum Block with Ropivacaine 7,5 mg/ml, 20 ml
干预措施: Ropivacaine (Drug)
TAP Block
A single shot unilateral TAP block with Ropivacaine 7,5 mg/ml, 20 ml
干预措施: Oksykodonhydroklorid (Drug)
TAP Block
A single shot unilateral TAP block with Ropivacaine 7,5 mg/ml, 20 ml
干预措施: Ondansetron and Droperidol (Drug)
TAP Block
A single shot unilateral TAP block with Ropivacaine 7,5 mg/ml, 20 ml
干预措施: Ropivacaine (Drug)
结局指标
主要结局
Opioid consumption measured as orale morphine equivalents.
时间窗: 0 - 4 hours
Differences in opioid consumption after four hours.
次要结局
- Postoperative nausea and vomiting(0 - 7 days postoperative.)
- Sedation scores(0 - 7 days postoperative.)
- Opioid consumption measured in orale morphine equivalents.(4 hours- 7 days postopertive.)