Analgesic Efficacy of Trans-muscular Quadratus Lumborum Block After Unilateral Inguinal Hernia Repair

Not Applicable

Completed

• Conditions: Postoperative Pain; Ultrasound Guided Nerve Block
• Interventions: Other: ultrasound guided quadratus lumborum block

• Registration Number: NCT03526731
• Lead Sponsor: Cairo University

Brief Summary

A significant component of pain experienced after abdominal surgery is related to incision of the abdominal wall and adequate analgesia can be a challenge.

The ultrasound-guided (USG) quadratus lumborum block QLB was first described by Rafael Blanco in a presentation at ESRA 2007 at the XXVI Annual ESRA Congress in Valencia, Spain. Blanco described a potential space posterior to the abdominal wall muscles and lateral to the quadratus lumborum muscle where Local anesthetics can be injected. This technique provide analgesia after abdominal surgery due to spread of LA from its lumbar deposition cranially into the thoracic paravertebral space where lateral and anterior cutaneous branches from Th7 to L1 can be blocked . This was proved by Carney et al. who found traces of contrast agent in the TPVS following application of this block A novel USG QL block is the transmuscular approach which relies on clearly identifiable sonographic bony landmarks, Where the needle is advanced through the QL muscle, penetrating the ventral proper fascia of the QL muscle and LA is finally injected between the QL and Psoas major (PM) muscle. The transmuscular QL block does not result in redundant antero-lateral spread of the injectate. This may indicate that lower volumes of LA potentially can be used and yet provide extensive thoracolumbar anesthesia.

This study was designed to compare the duration of analgesia provided by the original QLB and transmuscular QLB in patients undergoing surgical repair of unilateral inguinal hernia.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-05-04
• Study First Submitted QC: 2018-05-15
• Study First Posted: 2018-05-16
• Study Start: 2018-06-01
• Primary Completion: 2018-09-01
• Study Completion: 2018-12-01
• Status Verified: 2019-01
• Last Update Submitted: 2019-01-07
• Last Update Posted: 2019-01-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• ASA physical status I or II, scheduled for unilateral inguinal hernia repair

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Exclusion Criteria

• Patients with systemic hypertension, cardiovascular disease, cerebrovascular insufficiency, coagulation abnormities, renal or hepatic insufficiency, infection at the injection site, strangulated hernia and hypersensitivity to the local anesthetics

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group B (trans-muscular OLB-3)	ultrasound guided quadratus lumborum block	Local anesthetic will be injected between quadratus lumborum and psoas major after passing through the quadratus lumborum muscle guided by ultrasound.
Group A (original QLB-2):	ultrasound guided quadratus lumborum block	Local anesthetic will be injected between the quadratus lumborum muscle and the latissimus dorsi muscle guided by ultrasound.

Primary Outcome Measures

Name	Time	Method
duration of block	immediately after the end of LA injection till patients pain complaint (VAS > 3) over a period of 24 hours postoperative.

Trial Locations

Locations (1)

Abeer Ahmed; 🇪🇬 Cairo, Egypt