Validity of future risk prediction of electroencephalography (EEG) in complex febrile seizures.

Completed

• Conditions: febrile convulsion; febrile seizure; 10039911

• Registration Number: NL-OMON41841
• Lead Sponsor: Atrium Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

First febrile complex seizure
Age between 6 months and 5 years
Children with a normal mental and motor development

Exclusion Criteria

Diagnosis of epilepsy, febrile or afebrile seizures in history.
Diagnosed with an underlying neurological disease (like mental retardation, cerebral palsy, behavioral disorders)
Mental or motor impairment
Diagnosed with an intracerebral infection (e.g. meningitis, encephalitis)
Recent trauma capitis
Use of antiepileptic drugs
Born prematurely (before 32 weeks of gestation)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- Electroencephalography (EEG) results<br /><br>- Future febrile or afebrile seizures<br /><br>- Nature of seizures (febrile or afebrile), focal or generalized<br /><br>- Time to future (a)febrile seizure<br /><br><br /><br><br /><br><br /><br><br /><br><br /><br><br /><br><br /><br><br /><br><br /><br></p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Quality of life questionnaire: Infant Toddler Quality of Life QuestionnaireTM<br /><br>(ITQOL) 10<br /><br>- Impact of event scale 11<br /><br>- Development: WPPSI and Bayley-III-NL scores<br /><br>- Use of anti-epileptic drugs and side effects</p><br>