Consequence of Dexmedetomidine on Emergence Deliruim After Sevoflurane Anesthesia in Children With Cerebral Palsy

Phase 4

• Conditions: Emergence Deliruim; Cerebral Palsy
• Interventions: Drug: dexmedetomidine

• Registration Number: NCT02244515
• Lead Sponsor: Jin Ni

Brief Summary

The purpose of this study is to determine whether dexmedetomidine is effective in the treatment of emergence deliruim after sevoflurane anesthesia in children with cerebral palsy.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-06
• Status Verified: 2014-09
• Primary Completion: 2014-09
• Study First Submitted: 2014-09-17
• Study First Submitted QC: 2014-09-18
• Last Update Submitted: 2014-09-18
• Study First Posted: 2014-09-19
• Last Update Posted: 2014-09-19

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Non-quadriplegic (mono-,di-, hemiplegic) children with CP that are scheduled for elective Achilles-tendon lengthening procedure Guangzhou Women and Children's Medical Center, Guangzhou, China, with American Society of Anesthesiologists (ASA) physical status I or II.

Exclusion Criteria

Participants that displayed symptoms of sinus bradycardia and atrio-ventricular block, non-communicative severe developmental delay, seizure disorders, and treatment with seizure medications

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group D	dexmedetomidine	Five minutes prior to the commencement of the surgical procedure, Group D participants were administered dexmedetomidine 0.5μg•kg-1 diluted in 10 ml NaCI 0.9%

Primary Outcome Measures

Name	Time	Method
Heart rate	during surgical procedures
pediatric anesthesia emergence delirium (PAED) scale	during stay in postanesthesia care unit
systolic blood pressure	during surgical procedures
diastolic blood pressure	during surgical procedures