JPRN-UMIN000012008CompletedPhase 3
Randomized study of prochlorperazine for the prophylaxis of oxycodon induced nausea in patients with cancer related pain - Prophylaxis use of prochloroperazine
on-Profit Organization JORTC0 sites80 target enrollmentStarted: October 10, 2013Last updated:
Conditions
Trial Snapshot
- Phase
- Phase 3
- Status
- Completed
- Sponsor
- Enrollment
- 80
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 20years-old to ot applicable (—)
- Sex
- All
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1) Patients in need of anti-emesis medication (roughly >= NRS 3) Anti-emesis medication: prochlorperazine, metoclopramide, itopride, Mosapride citrate hydrate, Sulpiride, steroid 2) Episode of vomiting within 48hrs before registration 3) Patients with dementia, delirium, depressed level of consciousness, communication disorder due to aphasia, dyslexia, dysarthria etc 4) Patients with severe infection 5) Hypercalcemia (adjusted Ca conc (Ca mg/dL +(4-Alb)>11mg/dL) 6) Patient with ileus 7) Symptomatic brain metastasis 8) Patients who are planned to start chemotherapy or radiation therapy in purpose for palliation cancer pain, before the improvement of cancer pain by this protocol treatment. 9) Comorbidity which treatments take priority over cancer treatment. 10) Increase, decrease, cessation of hyptonic, anti-anxiety agent (tricyclic or tetracyclic, anti depressant, SNRI, SSRI, etc), psychotropic agent, anticonvulsant agent, ketamine hydrochloride) within 24hrs before registration 11) Patients taking adrenalin 12) Patients who are suspicious of sub-cortex brain disorder 13) Patients taking anticholinergic agent, triazole antifungal antibiotics 14) Patient who were judged to be ineligible by the doctor
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