Research on the Value of Genomics Research Based on Ultrasound Endoscopic Biopsy in the Differential Diagnosis and Prognostic Evaluation of Pancreatic Occupancy

• Conditions: Pancreatic Space Occupying

• Registration Number: NCT04986215
• Lead Sponsor: Changhai Hospital

Brief Summary

To clarify the value of genomic testing in the clinical diagnosis or prognosis of pancreatic space occupation, provide a basis for the selection of clinical diagnosis methods for pancreatic space occupation, optimize clinical management strategies, and improve the prognosis of patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-01
• Status Verified: 2021-07
• Study First Submitted: 2021-07-23
• Study First Submitted QC: 2021-07-29
• Last Update Submitted: 2021-07-29
• Study First Posted: 2021-08-02
• Last Update Posted: 2021-08-02
• Primary Completion: 2023-06-01
• Study Completion: 2023-09-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

1. Age 18-85, no gender limit
2. Imaging examinations suggest that the clear pancreas has clear space-occupying lesions
3. Admitted to our department, ready to undergo endoscopic ultrasound biopsy to confirm the diagnosis

Exclusion Criteria

1. There are contraindications for endoscopic ultrasound biopsy
2. Failed to join the group or refused follow-up due to various reasons

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Differential lncRNA detected by sequencing	June 2023	The diagnosis of lncRNA in pancreatic space occupying
Differential mRNA detected by sequencing	June 2023	The diagnosis of mRNA in pancreatic space occupying
Differential microRNA detected by sequencing	June 2023	The diagnosis of microRNA in pancreatic space occupying

Trial Locations

Locations (1)

Shanghai Changhai Hospital; 🇨🇳 Shanghai, Shanghai, China