Evaluation of the antimicrobial and clinical potency of copper nanoparticles gel against chlorhexidine gel after scaling and root planing (SRP) as a local drug delivery agent in patients with periodontitis.
Phase 2
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2022/07/044047
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Subjects should have at least 20 natural teeth.
2. Patients diagnosed with Generalized Periodontitis Stage 2 Grade B currently unstable without any risk factor (2017 World Workshop on the classification of periodontal and peri-implant diseases and conditions)
3. Patients ready to give informed consent and ready to collaborate with the study protocol
Exclusion Criteria
1. Pregnant/lactating mothers
2. Smokers/tobacco in any form
3. Patients who have undergone periodontal therapy, antibiotic or antiseptic therapy 6 months former to the study
4. Patients with bleeding disorders or under immunosuppressive chemotherapy
5. Any other systemic disease which can alter the course of periodontal disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Papillary Bleeding Index (PBI) by Saxer and MuhlemannTimepoint: Baseline, 1 month and 3 months
- Secondary Outcome Measures
Name Time Method Clinical attachment loss (CAL).Timepoint: Baseline, 1 month and 3 months;Modified Plaque Index (MPI) by Turesky et al modification of Quigley-Hein IndexTimepoint: Baseline, 1 month and 3 months;Probing pocket depth (PPD),Timepoint: Baseline, 1 month and 3 months