Clinical & antimicrobial effect of iodine potassium iodide
Phase 1
- Conditions
- Chronic apical periodontitis.
- Registration Number
- IRCT138903264196N1
- Lead Sponsor
- Shiraz university of Medical Scienced
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Only teeth with necrotic pulps as confirmed by negative response to sensitivity pulp tests were included in this study. Patients who received antibiotic therapy within the past 3 months were excluded from the study. Teeth with extensive caries or with fractures of the root/crown and with history of previous endodontic treatment did not consider in the study. Besides, cases showing periodontal pockets over 4 mm depth were also excluded.In the second phase,presence of sinus tract, swelling, mobility, tenderness to percussion or palpation and probing depth greater than the baseline measures will be recorded by an independent investigator and will serve as exclusion criteria
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bacterial load reduction in post-treatment samples in comparison to initial samples. Timepoint: At the end of trearment session. Method of measurement: Microbial colony forming unit( CFU).
- Secondary Outcome Measures
Name Time Method Any Change in periapical status from the baseline and presence or absence of clinical sign& symptoms after 30-months. Timepoint: 30-months. Method of measurement: Clinical and radiographical evaluation of treated patient after 30-months.