Mannitol for acute kidney injury during liver transplantatio
Phase 3
Completed
- Conditions
- Kidney Disease
- Registration Number
- PACTR202203622900599
- Lead Sponsor
- Mansoura University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 84
Inclusion Criteria
1. Adult (= 18 years old) patients
2. Either sex
3. Undergoing living donor liver transplantation with right lobe graft from family-related donors.
Exclusion Criteria
1. Acute fulminant hepatitis
2. Estimated Graft/Recipient Weight ratio (GRWR) < 0.8
3. Portal hypertension with mean pulmonary blood pressure > 35 mmHg
4. Preoperative serum creatinine (SCr) > 1.4 mg/dl or dialysis within the last 3 months
5. Diabetes Mellitus (> 10 years)
6. Preoperative serum sodium [Na+] < 125 mEq/L and serum potassium [K+] > 5.5 mEq/L
7. Intra-operative massive blood transfusion (replacement of > 50% of total blood volume in < 3 hours)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method