Endometriosis and ATR-FTIR Spectroscopy
- Conditions
- EndometriomasEndometriosis
- Registration Number
- NCT06426420
- Lead Sponsor
- Federal University of Espirito Santo
- Brief Summary
The goal of this study is to explore the use of mid-infrared spectroscopy (ATR-FTIR) as a detection tool for endometriosis in urine.
- Detailed Description
Endometriosis is a chronic gynecological disease that is considered debilitating and multifactorial. Its diagnosis is invasive and can be prolonged due to non-specific symptoms and erroneous or late investigations, which can lead to delays and impair the provision of adequate treatment.
ATR-FTIR Spectroscopy is a non-invasive technique with the capability to identify the chemical composition and molecular changes of samples through its interaction with mid-infrared radiation. The aim of this work is to develop a rapid test for the detection of endometriosis in urine samples using spectroscopy and machine learning algorithms.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Female
- Target Recruitment
- 600
- Female
- Pelvic pain complain
- Age under 18 or above 55
- Lack of informed consent
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Spectroscopy Reliability (diagnostic metrics) 1 year The primary outcome is the evaluation of specificity, sensitivity and accuracy of the diagnostic. Acceptable diagnostic metrics must be comparable to MRI, which will demonstrate if spectroscopy can discriminate between negative and positive endometriosis patients.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Cassiano Antonio Moraes at Federal Univeristy Of Espírito Santo
🇧🇷Vitória, Espírito Santo, Brazil
University Hospital Cassiano Antonio Moraes at Federal Univeristy Of Espírito Santo🇧🇷Vitória, Espírito Santo, BrazilNeide A Boldrini, phDPrincipal InvestigatorMara RB Barcelos, phDPrincipal Investigator