Comparative trial of morphine mouthwash and ketamine mouthwash for oral mucositis
Phase 2
- Conditions
- Health Condition 1: C81-C96- Malignant neoplasms of lymphoid, hematopoietic and related tissue
- Registration Number
- CTRI/2024/01/062050
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
18 years of age or older
Received at least one dose of chemotherapy
Having oral mucositis pain score on NRS more than or equal to 6
Able to do mouthwash without swallowing
Able to sign the informed consent
Exclusion Criteria
Any documented previous hypersensitivity to ketamine
Local oral infection
Received prior ketamine or morphine doses by any route within 48 h of study initiation.
Pregnant or breastfeeding.
Patients with hypertension, history of epilepsy and any cardiac conditions.
History of any psychiatric disorder that is at the risk of exacerbation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method