A Randomized Controlled Trial Comparing Deep Versus Moderate Neuromuscular Block - in Low Pressure Pneumoperitoneum - to Optimize the Surgical Conditions During Laparoscopic Donor Nephrectomy

Radboud University Medical Center1 site in 1 country34 target enrollmentApril 2015

ConditionsNephrostomy; Complications Pneumoperitoneum Observation of Neuromuscular Block

Overview

Phase: Phase 4
Intervention: Not specified
Conditions: Nephrostomy; Complications
Sponsor: Radboud University Medical Center
Enrollment: 34
Locations: 1
Primary Endpoint: Mean surgical rating score
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Live kidney transplantation is first choice for patients with end-stage kidney disease. Therefore, the safety and well-being of kidneys donors are highly important objectives in live kidney donation. Low pressure pneumoperitoneum can decrease postoperative pain and therefore also concomitant use of opioids.

Detailed Description

However low pressure pneumoperitoneum can also decrease peri-operative conditions. In this trial the researchers will investigate whether peri-operative conditions during low pressure pneumoperitoneum can be optimized by the use of deep neuromuscular block.

Registry

clinicaltrials.gov

Start Date

April 2015

End Date

February 2016

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Radboud University Medical Center

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•obtained informed consent
•age over 18 years

Exclusion Criteria

•chronic use of analgesics or psychotropic drugs
•use of non-steroidal anti-inflammatory drugs shorter than 5 days before surgery
•known or suspect allergy to rocuronium or sugammadex
•significant liver or renal dysfunction
•pregnant or breastfeeding