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A Trial Comparing Deep Versus Moderate Neuromuscular Block - in Low Pressure Pneumoperitoneum

Phase 4
Completed
Conditions
Pneumoperitoneum
Observation of Neuromuscular Block
Nephrostomy; Complications
Registration Number
NCT02602964
Lead Sponsor
Radboud University Medical Center
Brief Summary

Live kidney transplantation is first choice for patients with end-stage kidney disease. Therefore, the safety and well-being of kidneys donors are highly important objectives in live kidney donation. Low pressure pneumoperitoneum can decrease postoperative pain and therefore also concomitant use of opioids.

Detailed Description

However low pressure pneumoperitoneum can also decrease peri-operative conditions. In this trial the researchers will investigate whether peri-operative conditions during low pressure pneumoperitoneum can be optimized by the use of deep neuromuscular block.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
34
Inclusion Criteria
  • obtained informed consent
  • age over 18 years
Exclusion Criteria
  • chronic use of analgesics or psychotropic drugs
  • use of non-steroidal anti-inflammatory drugs shorter than 5 days before surgery
  • known or suspect allergy to rocuronium or sugammadex
  • significant liver or renal dysfunction
  • pregnant or breastfeeding

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Mean surgical rating scoreperioperative
Secondary Outcome Measures
NameTimeMethod
Length of pneumoperitoneumperioperative
Intra-operative complicationsperioperative
Conversion to standard pressure pneumoperitoneumperioperative

Trial Locations

Locations (1)

Radboud University Medical Center

🇳🇱

Nijmegen, Netherlands

Radboud University Medical Center
🇳🇱Nijmegen, Netherlands

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