A Trial Comparing Deep Versus Moderate Neuromuscular Block - in Low Pressure Pneumoperitoneum
- Conditions
- PneumoperitoneumObservation of Neuromuscular BlockNephrostomy; Complications
- Registration Number
- NCT02602964
- Lead Sponsor
- Radboud University Medical Center
- Brief Summary
Live kidney transplantation is first choice for patients with end-stage kidney disease. Therefore, the safety and well-being of kidneys donors are highly important objectives in live kidney donation. Low pressure pneumoperitoneum can decrease postoperative pain and therefore also concomitant use of opioids.
- Detailed Description
However low pressure pneumoperitoneum can also decrease peri-operative conditions. In this trial the researchers will investigate whether peri-operative conditions during low pressure pneumoperitoneum can be optimized by the use of deep neuromuscular block.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 34
- obtained informed consent
- age over 18 years
- chronic use of analgesics or psychotropic drugs
- use of non-steroidal anti-inflammatory drugs shorter than 5 days before surgery
- known or suspect allergy to rocuronium or sugammadex
- significant liver or renal dysfunction
- pregnant or breastfeeding
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Mean surgical rating score perioperative
- Secondary Outcome Measures
Name Time Method Length of pneumoperitoneum perioperative Intra-operative complications perioperative Conversion to standard pressure pneumoperitoneum perioperative
Related Research Topics
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Trial Locations
- Locations (1)
Radboud University Medical Center
🇳🇱Nijmegen, Netherlands
Radboud University Medical Center🇳🇱Nijmegen, Netherlands