Using Visual Arrays to Support Understanding of Genetic Risk

Not Applicable

Not yet recruiting

• Conditions: Decision Aid

• Registration Number: NCT06905990
• Lead Sponsor: Boston College

Brief Summary

The goal of this study is to understand how people understand risk from genetic testing. The investigators want to understand what visual aid best helps people accurately assess risk. The investigators also want to understand how people relate risk to their health. The main questions the study aims to answer are:

1. Which visual aid most accurately show genetic risk?

2. How do people perceive risk related to genetic test results?

3. What factors are associated with people discussing their results with family?

Participants will:

1. receive of of two visual aids showing risk

2. state their estimation of risk

3. answer questions about how they feel about risk and sharing information with family

Detailed Description

This study aims to determine how visual aids help people most accurately interpret risk from genetic test results. The study also examines how people perceive risk by drawing on the Tripartite Risk Model. Last, the study examines factors that are associated with intention to share genetic test results with family members.

Participants will provide brief sociodemographic information, complete brief health literacy and numeracy assessments, and questions about how they perceive risk. Participants will be informed of a genetic testing scenario and will receive one of two visual aids. After reviewing the visual aid, participants will state the risk shown in the visual aid and will answer questions about their perceived risk and sharing results with family members (blood relatives).

Study Timeline

• Status Verified: 2025-03
• Study First Submitted: 2025-03-19
• Study First Submitted QC: 2025-03-25
• Last Update Submitted: 2025-03-25
• Study Start: 2025-04-01
• Study First Posted: 2025-04-02
• Last Update Posted: 2025-04-02
• Primary Completion: 2025-05-31
• Study Completion: 2025-06-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 1200

Inclusion Criteria

• ability to read and understand English
• opt-in consent

Exclusion Criteria

• incorrect responses to validation questions

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Risk Accuracy	immediately after the intervention	closest approximation to risk percentage depicted in the visual array

Secondary Outcome Measures

Name	Time	Method
Risk Perceptions	immediately after the intervention	Perceptions based on the Tripartite Risk Model
Communication intent	immediately after the intervention	Intent to communicate risk to blood relatives