TCTR20190103001尚未招募未知
euro-immune, neuro-oxidative and neuro-nitrosative pathways in association with LINE1/Alu methylation in acute schizophrenia
the Ratchadapisek Somphot Fund0 个研究点目标入组 90 人开始时间: 2019年1月3日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 65 Years（—）
- 性别
- All
入选标准
- •1.An acute phase of schizophrenia (both new onset schizophrenia patients and patients with acute exacerbations) while being able to cooperate with the study protocol (therefore a window of 10 days from admission is allowed). Thus we will include patients in an acute state with positive symptom exacerbations or psychotic decompensation or disorganization.
- •2.Meet the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Text-Revised and DSM-5 criteria for schizophrenia.
排除标准
- •1.A current and life-time diagnosis of axis-I DSM IV-TR / DSM-5 disorders other than schizophrenia, e.g. major depression or bipolar disorder, substance use disorders, psycho-organic disorders, etc.
- •Exclusion criteria for patients and controls are:
- •1.Medical illnesses, such as inflammatory bowel disease and rheumatoid arthritis; COPD; neurodegenerative disorders; diabetes type 1 and 2, dementia, Parkinson’s and Huntington’s disease, stroke, etc.
- •2.Treatments with immunomodulatory drugs, including glucocorticoids; and c) alcohol abuse.
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