The effect of melatonin in the prevention of retinopathy of prematurity

Phase 3

• Conditions: Retinopathy of Prematurity.; Retinopathy of prematurity; H35.1

• Registration Number: IRCT20211226053528N2
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Parents satisfaction to participate in the study
Premature newborns under 34 weeks
Lack of congenital anomalies
Lack of genetic disorder, metabolic disorder or suffering from TORCH
Lack of intraventricular hemorrhage (grade 3 and 4)

Exclusion Criteria

Intraventricular hemorrhage (grade 3 and 4) during patients follow up
Incidence of gastrointestinal complications such as NEC during treatment if it is not possible to take the medicine orally.
Taking less than 14 days of melatonin

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Stopping of abnormal blood vessels formation in the retina. Timepoint: End of 37 weeks and end of 44 weeks. Method of measurement: Examination by retina fellowship and with ophthalmoscope.