Influence of different resistance training programs on morphological adaptations of the anterior cruciate ligament and the M. quadriceps femoris in males and females
- Conditions
- Prevention of anterior cruciate ligament injuries
- Registration Number
- DRKS00031249
- Lead Sponsor
- Orthopädische Klinik und Poliklinik, Universitätsmedizin Rostock
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
(1)Healthy female and male participants
(2)Untrained (no strength training on regular basis during the last year)
(1)Metal-containing or electrically conductive objects in the body (e.g., spiral, solid braces, clips, vessel clips, pacemakers or joint prostheses).
(2)Injuries of the anterior cruciate ligament or other ligaments, menisci, cartilage of the knee joint
(3)Regular smokers
(4)Cachexia or obesity (BMI < 19 or > 30 kg/m²).
(5)Active or suspected infection
(6)Severe heart failure and COPD or a high risk of thrombosis
(7)Acute spinal disease (e.g., lumboischialgia, disc prolapse, spinal stenosis).
(8)Severe joint, muscular or systemic diseases
(9)Neurological diseases affecting cognition
(10)Manifest tumour or other severe chronical diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome of this study is the alteration of the anterior cruciate ligament volume. It is measured before and after the intervention period (16 weeks) using magnetic resonance imaging (MRI).
- Secondary Outcome Measures
Name Time Method Additional outcomes measured before and after the intervention period are: muscle volume (MRI) and maximal voluntary muscle strength of the thigh muscles (by means of dynamometry) as well as the maximal muscle activity during this maximum voluntary contraction (by means of electromyography).