Desensitization wheat
Early Phase 1
- Conditions
- Food allergy.Other adverse food reactions, not elsewhere classified
- Registration Number
- IRCT2013102015076N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 5
Inclusion Criteria
patients with type1 allergic reaction to wheat flour; age between 2-18 years old; normal physical examination; no sever asthma; no cardiac diseas, no other chronic diseases and informed consent was taken from patients.
Exclusion criteria: 1-patients who did not permit us to enter them in the study. 2-patients with hypersensitivity reactions other than type one reaction. 3-patients having cardiac diseases (heart failure, heart valve insufficiency, severe valve stenosis, myocardial infarction) 4- patients with severe pulmonary diseases (severe asthma, chronic obstructive pulmonary disease, severe chronic bronchiolitis). 5-patients age less than 2 or more than 18 years old.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Desentizition with wheat. Timepoint: no urtrica in examination.no asthma ,no eczema. Method of measurement: physician examination and parent.
- Secondary Outcome Measures
Name Time Method Eosinophilia. Timepoint: befor and after portocol. Method of measurement: see cbcdiff.;Prick test. Timepoint: befor &after portocol. Method of measurement: study and see wheal.;Eosinophilia in nasal smear. Timepoint: befor and after portocol desentization. Method of measurement: see in nasal smear.;IgE level in serum. Timepoint: befor and after portocol desentization. Method of measurement: elisia.;Wheat spcific IgE level in serum. Timepoint: befor and after portocol desentization. Method of measurement: elisia.