Comparasion of Dexamethasone and Dexmedetomidine as an additive to Lignocaine in Inferior Alveolar Nerve Block in reducing pain after lower impacted third molar surgery
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/03/041276
- Lead Sponsor
- Sharad Pawar Dental College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Individuals with ASA Group I status
2. Individuals between 18 to 40 years
3. Presence of unilateral Impacted Mandibular Third Molar having moderate to difficult, difficulty index (Modified Pedersonâ??s Scoring)
1. History of drug dependence
2. Patients with systemic disease such as HTN, DM, blood dyscrasias, immunocompromised status.
3. Patients who chronic smokers
4. Patients on cardioselective antihypertensive drugs.
5. Patients with allergy to local anaesthetic agents used in the study
6. Pregnant and nursing mothers
7. Females on oral contraceptives
8. Patients undergoing treatment with antibiotics, anti-inflammatory drugs
9. Presence of any local infection like pericoronitis/pterygomandibular space infection
10. Presence of any persistent facial pain on the intervention side
11. Radiologic evidence of Inferior alveolar canal approximation
12. Patients with Congenital Heart Disease.
13. Patients who are have any psychiatric illness.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)Duration of postoperative analgesia <br/ ><br>2)Latency /Onset of anaesthesia <br/ ><br>3) Pain threshold <br/ ><br>4) Post-operative severity of trismus <br/ ><br>5) Post-operative extent of facial swelling <br/ ><br>6) Pain measurement at specified intervals <br/ ><br>7) Measurement of pain and physical quality of life using PoSSe Scale <br/ ><br>8) Number of analgesics consumedTimepoint: At baseline, 2nd day and 7th day
- Secondary Outcome Measures
Name Time Method Post-operative extent of facial swelling <br/ ><br>6) Pain measurement at specified intervals <br/ ><br>7) Measurement of pain and physical quality of life using PoSSe Scale <br/ ><br>8) Number of analgesics consumedTimepoint: intra-operative, immediate post operative, 2nd and 7th day