MedPath

Periprosthetic Bone Mineral Density Changes After Implantation Of A Short Hip Stem Compared To A Straight Stem

Not Applicable
Conditions
Osteoarthritis, Hip
Interventions
Procedure: Total Hip Arthroplasty
Registration Number
NCT03147131
Lead Sponsor
University Hospital Ulm
Brief Summary

The aim of this study is to evaluate periprosthetic bone mineral density (BMD) changes in the proximal femur after implantation of the Fitmore compared to the CLS stem.

Detailed Description

After power analysis, 140 consecutive patients were prospectively included in the randomisation protocol receiving either a Fitmore short or a CLS straight stem. The short stem was assigned in 57 (37% females) cases and the straight stem in 83 (38% females) hips. Periprosthetic bone mineral density was measured before surgery, 7 days, 3, 12 and 60 months postoperatively, using dual energy x-ray absorptiometry (DEXA). The results of the first postoperative measurement served as the baseline value. Because of the different length of the two prostheses we used adapted Gruen zones to divide the periprosthetic bone in seven regions of interest (ROI) with equal length in the proximal zones 1,2,6 and 7, only the regions 3 and 5 featured different sizes. Clinical results were recorded using the WOMAC and the Harris hip score (HHS).

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
126
Inclusion Criteria
  • Primary or secondary osteoarthritis of the hip
  • written informed consent
  • indication for cementless total hip arthroplasty
Exclusion Criteria
  • previous surgery in the same hip
  • femoral fracture
  • metabolic bone disease
  • drugs affecting bone quality
  • contralateral THA within the study period
  • infectious disease or bony tumor

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Fitmore short stemTotal Hip ArthroplastyIntervention: Total hip arthroplasty with an uncemented femoral short stem, the Fitmore short stem (Zimmer, Warsaw, USA). Furthermore, an uncemented cup (Allofit, Zimmer, Warzaw, USA). Device: Fitmore Short Stem
CLS straight stemTotal Hip ArthroplastyIntervention: Total hip arthroplasty with an uncemented femoral straight stem, the CLS short stem (Zimmer, Warsaw, USA).Furthermore, an uncemented cup (Allofit, Zimmer, Warzaw, USA). Device: CLS Straight Stem
Primary Outcome Measures
NameTimeMethod
Stem specific stress shielding of a short compared to a straight hip stemFive years postoperatively

Periprosthetic Bone Mineral Density changes around a total hip arthroplasty stem

Secondary Outcome Measures
NameTimeMethod
Clinical Outcome after short compared to straight stem THAFive years postoperatively

Clinical outcome measured with the Harris Hip Score and the WOMAC

© Copyright 2025. All Rights Reserved by MedPath