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Clinical Trials/NCT05635526
NCT05635526
Completed
Not Applicable

Assessment of Corneal Biomechanics With the Corvis ST in Different Age of Myopia With Orthokeratology

Tianjin Eye Hospital1 site in 1 country134 target enrollmentJune 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Myopia
Sponsor
Tianjin Eye Hospital
Enrollment
134
Locations
1
Primary Endpoint
The change of dynamic corneal response (DCR)
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The present research focused on the effect of the age for the corneal biomechanics of low and moderate myopia patients after wearing orthokeratology (OK lens). According to age, the included cases were divided into 3 groups. Through the analysis of corneal biomechanical parameters, further learn the influence of OK lens on the patient cornea. It would help ophthalmologist and optometrist find out the potential issue and reach a better control result.

Detailed Description

The present research focused on the effect of the age for the corneal biomechanics of low and moderate myopia patients after wearing orthokeratology (OK lens). According to age, the included cases were divided into 3 groups: Ⅰ (8-12 years old), Ⅱ (13-16 years old), Ⅲ (over 16 years old). The OK lenses used in the present study are of the same design (Euclid Systems Orthokeratology; Euclid System, Herndon, VA, USA). The base line (Day 0) and different follow-up time point (Day 1, Week 1, Week 2, Month 1, Month 3, and Month 6) of dynamic corneal response (DCR) (including 19 items) of the patients derived by Corvis ST were collected. The difference between before and after wearing OK Lens and the changes of parameters among the three groups were both analyzed. And the correlation between axis length (AL) and the 19 parameters also was analyzed. Through the analysis of corneal biomechanical parameters, further learn the influence of OK lens on the patient cornea. It would help ophthalmologist and optometrist find out the potential issue and reach a better control result.

Registry
clinicaltrials.gov
Start Date
June 1, 2020
End Date
October 1, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • age from 8 to 40 years old
  • spherical equivalent(SE) was range from -1.00D to -5.00D
  • conform to the standard of wearing orthokeratology lens

Exclusion Criteria

  • ocular diseases and systemic diseases
  • visual acuity was less than 20/20
  • unable to follow visitors on time

Outcomes

Primary Outcomes

The change of dynamic corneal response (DCR)

Time Frame: The change of baseline and 1 day, 1 week, 2 weeks, 1 month, 3 months, and 6 months

The axial length was measured by Corvis ST

Secondary Outcomes

  • The change of axial length(The change of baseline and 6 months)

Study Sites (1)

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