Antihypertensive Drug Treatment Decisions Based on Home Blood Pressure Monitoring
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- Intermediate target organ damage (Left Ventricular Hypertrophy, Microalbuminuria, carotid-femoral Pulse Wave Velocity, Central blood pressure)
研究概览
简要总结
This is a prospective randomized study with two arms: the Conventional and Ambulatory blood pressure monitoring arm and the Home blood pressure monitoring arm. The study will include both previously treated and untreated individuals.
Before randomization and in the end of the study, measurements will be performed using all three blood pressure monitoring methods (Conventional, Ambulatory and Home) as well as assessment of target organ damage (microalbuminuria, electrocardiogram, echocardiogram, carotid-femoral pulse wave velocity and central blood pressure).
The participants will be randomized into one of the two arms. Diagnosis and titration will be decided according to either Conventional and Ambulatory blood pressure measurements or according to Home blood pressure measurements. Subjects will be followed up for one year.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Untreated hypertensive adults
- •Treated hypertensive adults with uncontrolled blood pressure
排除标准
- •Stage III Hypertension
- •Secondary Hypertension
- •Cardiovascular or Renal disease
- •Uncontrolled Diabetes
结局指标
主要结局
Intermediate target organ damage (Left Ventricular Hypertrophy, Microalbuminuria, carotid-femoral Pulse Wave Velocity, Central blood pressure)
时间窗: Baseline and 12 months
次要结局
- Blood Pressure Control, Cost-Effectiveness(Baseline and 12 months)
研究者
George S. Stergiou
Associate Professor of Medicine and Hypertension
University of Athens