Research of the Application of Triple Antibiotic Paste in Primary Teeth With Pericpical Periodontitis
Not Applicable
- Conditions
- Periapical Diseases
- Interventions
- Drug: Metronidazole-Ciprofloxacin gatifloxacin-Clindamycin paste
- Registration Number
- NCT02196740
- Lead Sponsor
- Lin Jiacheng
- Brief Summary
The triple antibiotic paste is widely used in young permanent teeth and permanent teeth root canal therapy with excellent antiantimicrobial effect.We hypothesize that its application in the treatment of periapical periodontitis of deciduous teeth is superior to other drugs currently in use as creosote.
- Detailed Description
We design to collect a group of patients presenting primary teeth with periapical periodontitis in certain criterion. We will divide the patients into two groups randomly.One group will get treated with triple antibiotic paste while the other with creosote.We want to evaluate the short-term and long-term effects of the two groups to get a conclusion of the clinical value of triple antibiotic paste.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- clinical diagnosis of periapical periodontitis
- must be primary teeth
- must be 3~8 years old
- the permanent tooth germ is complete and didnot be involved
Exclusion Criteria
- blood disease
- residual root that is advised to extract
- serious periodontitis
- allergy to the triple antibiotic paste
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Triple Antibiotic Paste Metronidazole-Ciprofloxacin gatifloxacin-Clindamycin paste Triple Antibiotic Paste,once,three weeks creosote,none creosote creosote Creosote ，once，three weeks Triple Antibiotic Paste ，none
- Primary Outcome Measures
Name Time Method Evidence of lesion healing confirmed by cone beam computed tomography and X-rays 1 year
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Jicheng Lin
🇨🇳Guangzhou, Guangdong, China