Comparison of changes in Orexin-A levels in propofol-remifentanil anesthesia with sevoflurane-remifentanil anesthesia undergoing ear surgery.
- Conditions
- ear disease
- Registration Number
- JPRN-UMIN000037648
- Lead Sponsor
- Department of Anesthesiology and Intensive care, Faculty of Medicine, University of Miyazaki.
- Brief Summary
The extubation times were faster in the TIVA group than in the SEV group. At the emergence state, plasma orexin-A increased in both the TIVA and SEV groups, as compared with their corresponding T0 levels. There were no significant differences in the plasma orexin-A values of the TIVA and SEV groups at each corresponding time point.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 41
Not provided
Patients were excluded who had used analgesics, sedatives, or antidepressants within 72 h prior to surgery; had a history of obstructive sleep apnea syndrome, chronic obstructive pulmonary disease, diabetes mellitus, endocrine disorder, or neurological disease; had a hepatic, renal, or psychological disorder; whose operation time was < 2 hours or > 5 hours; were < 20 or > 70 years old, or had a BMI < 18.5 or > 25.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method