The efficacy of intra-articular triamcinolone acetonide 10 mg versus 40 mg in patients with osteoarthritis knee, a non-inferiority, randomized, controlled, double-blind study.

Phase 3

Recruiting

• Conditions: Primary osteoarthritis of knee.; Osteoarthritis of knee; Triamcinolone acetonide; Intraarticular steroid injection

• Registration Number: TCTR20210224002
• Lead Sponsor: Department of internal medicine, Phramongkutklao college of medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-02-23
• Study Start: 2021-02-24
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 208

Inclusion Criteria

Patient with primary osteoarthritis of knee according to ACR criteria and age over 50 years old, which fail oral pain medication or contraindicated.

Exclusion Criteria

Contraindicated for intraarticular steroid injection, infection, bleeding diathesis.
Previous intraarticular steroid injection in previous 3 months
Secondary osteoarthritis of knee
Patient who takes systemic steroid
Knee with prosthesis
Patient with schedules for TKA in 3 months from randomization

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score by VAS 4 and 12 weeks VAS

Secondary Outcome Measures

Name	Time	Method
Thai WOMAC score 4 and 12 weeks Questionnaire,Thai KOOS 4 and 12 weeks Questionnaire,EQ5D 4 and 12 weeks Questionnaire,Global VAS 4 and 12 weeks VAS,Timed 20m walk 4 and 12 weeks Duration,Chair stand test 4 and 12 weeks Number