EXPLICIT-stroke
- Conditions
- cerebrovascular accidentstrokeberoerte
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 180
Inclusion Criteria
1. First ever ischemic lesion in territory of MCA
2. Mono- or hemiparesis (NIHSS item 5a&b score 1-4)
Exclusion Criteria
1. Trombolysis (rTPA, alteplase) with positive effect
2. Pacemaker or metallic implants
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - ARAT (A projects)<br /><br>- Focussing of cortical activity in original target area (fMRI, B1 project)<br /><br>- Integrity of corticospinal tract (TMS)<br /><br>- Trunk movement in standard reaching task (B2 project)<br /><br>- Neuromechanics, i.e. stiffness, motor function (paresis) and control (reflex gains and modulation) around wrist joint (B3 project)
- Secondary Outcome Measures
Name Time Method - Modified Ashworth score<br /><br>- Wolf motor function test<br /><br>- Frenchay arm test<br /><br>- Motoricity index<br /><br>- Brunnstrom Fugl Meyer arm-hand test<br /><br>- Nine hole peg test<br /><br>- Erasmus MC modification of Nottingham sensory assessment<br /><br>- Stroke impact scale 3.0<br /><br>- Nottingham extended ADL<br /><br>- Motor activity log<br /><br>- O-letter cancelation test<br /><br>- Barthel index<br /><br>