Homeopathic medicines for knee pai

Phase 2

Conditions: Health Condition 1: M179- Osteoarthritis of knee, unspecified

Registration Number: CTRI/2019/10/021670

Lead Sponsor: D N De Homoeopathic Medical College Hospital Govt of West Bengal

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1. Age 35-70 years

2. Both sexes

3. Diagnosed knee osteoarthritis as per American College of Rheumatology (ACR) clinical/radiographic classification criteria:

a) Knee pain

b) At least 1 of 3: age more than 50 years, stiffness less than 30 min, and crepitus on knee motion

c) Osteophytes on knee x-ray

4. Patients already undergoing regular oral or topical analgesics or NSAID therapy for painful episodes of osteoarthritis, provided the medications are stopped completely at least 2 weeks prior study entry

5. Literate patients; can read Bengali, Hindi or English

6. Providing written informed consent.

Exclusion Criteria

1. Severe degeneration of knee joint with marked joint narrowing, varus, or valgus deformity of knee ( >12Â°), evidenced by imaging or other evidences and requiring surgical intervention

2. Non-ambulant patients

3. Self-reported joint disorders other than osteoarthritis (e.g., inflammatory joint disease, specific arthropathy, hyperuricaemia and/or gout, severe axis deviations or instabilities, joint or skin infections, joint prostheses of the lower limbs)

4. Intra-articular injections within 2 weeks before study entry

5. Transplanted knees

6. Recent significant knee surgery within last 6 months

7. Patients who are too sick for consultation

8. Unwilling to take part and not giving consent to join the study

9. Unable to read patient information sheet

10. Diagnosed cases of unstable mental or psychiatric illness or other uncontrolled or life-threatening illness affecting quality of life

11. Pregnancy and lactation

12. Substance abuse and/or dependence

13. Self-reported immune-compromised state, and

14. Undergoing homeopathic treatment for any chronic disease within last 6 months

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Knee injury and Osteoarthritis Outcome Score (KOOS)Timepoint: At baseline, every month up to 3 months

Secondary Outcome Measures

Name	Time	Method
EQ-5D-5L questionnaireTimepoint: At baseline, every month up to 3 months;Frequency of add-on Paracetamol and/or NSAIDs (oral/topical) useTimepoint: At baseline, every month up to 3 months