Effect of Aerobic Training and Calorie Restriction on Hormonal and Metabolic Factors Related to Fatty Liver in Postmenopausal Women with NAFLD
Not Applicable
Completed
- Conditions
- on-Alcoholic Fatty Liver Disease.Nonalcoholic steatohepatitis (NASH)K75.81
- Registration Number
- IRCT20190408043203N1
- Lead Sponsor
- Vice-Chancellor for Research of University of Guilan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 24
Inclusion Criteria
Overweight Postmenopausal Women with NAFLD
Exclusion Criteria
Weight Changing over 2 kg over the past 6 months
Smoking
Alcohol consumption more than 30 grams per day
Use of supplementary pills and special dietary
Cardiovascular disease And respiratory diseases
Orthopedic problems
Prohibition of participation in sports activities
Regular exercise in the past year (at least 3 days a week)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Estrogen Levels. Timepoint: Before and after intervention. Method of measurement: Blood Sample Analysis.;Insulin Resistance Index. Timepoint: Before and after intervention. Method of measurement: Insulin Resistance Index Formula with Insulin and Glucose Levels.;Hepatic Fat. Timepoint: Before and after intervention. Method of measurement: elastography.;Glucose Levels. Timepoint: Before and after intervention. Method of measurement: Blood Sample Analysis.;Insulin Levels. Timepoint: Before and after intervention. Method of measurement: Blood Sample Analysis.;Liver Enzymes. Timepoint: Before and after intervention. Method of measurement: Blood Sample Analysis.;Fetuin A Levels. Timepoint: Before and after intervention. Method of measurement: Blood Sample Analysis.;Lipid profile. Timepoint: Before and after intervention. Method of measurement: Blood Sample Analysis.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link aerobic training and calorie restriction to NAFLD improvement in postmenopausal women?
How does IRCT20190408043203N1 compare to standard therapies like GLP-1 agonists in managing NASH-related metabolic factors?
Which biomarkers could predict response to aerobic training in postmenopausal NAFLD patients with insulin resistance?
What are the potential adverse events of calorie restriction in postmenopausal women with K75.81 and how are they managed?
Are there synergistic effects between aerobic exercise and pharmacological agents like SGLT2 inhibitors in treating NASH?