Effects of Motive-Oriented Therapeutic Relationship in the Early-Phase Treatment of Borderline Personality Disorder

Not Applicable

Completed

• Conditions: Borderline Personality Disorder
• Interventions: Behavioral: Psychiatric Management; Behavioral: Motive-oriented therapeutic relationship/Plan Analysis

• Registration Number: NCT01896024
• Lead Sponsor: University of Lausanne Hospitals

Brief Summary

The present research aims at examining the effectiveness of a specific set of therapist relational interventions and attitudes, called the Motive-Oriented Therapeutic Relationship (MOTR), based on Plan Analysis (Caspar, 2007) in the early-phase treatment of patients diagnosed with Borderline Personality Disorder.

The investigators intend to include N = 80 outpatients diagnosed with Borderline Personality Disorder, consulting at the Outpatient Personality Disorder Program of the Karl Jaspers Clinical Unit, in collaboration with the Institute of Psychotherapy, at the Department of Psychiatry-CHUV, University of Lausanne and in collaboration with the University of Berne, Switzerland. Patients are assigned by chance to two treatment conditions 1) Control condition (General Psychiatric Management; Gunderson \& Links, 2008) and 2) MOTR-condition. The investigators hypothesize better results in the MOTR-condition, as compared to the control condition in terms of symptom reduction pre-post.

The conduct of the study represents a significant contribution to the understanding and enhancement of relationship aspects in the treatment of patients diagnosed with Borderline Personality Disorder which may be of potential benefit for these patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-06
• Primary Completion: 2013-05
• Study First Submitted: 2013-07-05
• Study First Submitted QC: 2013-07-10
• Study First Posted: 2013-07-11
• Study Completion: 2014-04
• Status Verified: 2014-12
• Last Update Submitted: 2014-12-01
• Last Update Posted: 2014-12-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 85

Inclusion Criteria

• DSM-IV Borderline Personality Disorder;
• between 18 and 65 yrs of age

Exclusion Criteria

• DSM-IV psychotic disorders,
• mental retardation,
• substance abuse in the forefront

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
GPM plus Motive-Oriented Therapeutic Relationship	Motive-oriented therapeutic relationship/Plan Analysis	use of Plan Analysis and Motive-oriented therapeutic relationship, as add-on variable to GPM
GPM plus Motive-Oriented Therapeutic Relationship	Psychiatric Management	use of Plan Analysis and Motive-oriented therapeutic relationship, as add-on variable to GPM
General Psychiatric Management (GPM; Gunderson & Links, 2008)	Psychiatric Management	psychodynamic-psychiatric treatment for borderline personality disorder

Primary Outcome Measures

Name	Time	Method
Outcome Questionnaire -45.2 (Lambert et al., 2004)	3 months	pre- post- intervention in a randomized controlle trial; measure of symptom reduction over 3 months

Secondary Outcome Measures

Name	Time	Method
Inventory of Interpersonal Problems (Horowitz et al., 1988)	3 months	Measure of interpersonal problems after 3 months of therapy

Trial Locations

Locations (1)

Department of Psychiatry-CHUV, University of Lausanne; 🇨🇭 Lausanne, VD, Switzerland