Comparison of pain relief after lower abdominal surgeries using dexmedetomidine and nalbuphine with bupivacaine in spinal anaesthesia

Not yet recruiting

• Conditions: Inflammatory disease of cervix uteri, (2) ICD-10 Condition: K36||Other appendicitis,

• Registration Number: CTRI/2020/06/026160
• Lead Sponsor: J L N Medical College and Hospital

Brief Summary

The aim of our study is to compare the efficacy of intrathecal dexmedetomidine 10 microgram versus nalbuphine hydrochloride 1 milligram as an adjuvant to 0.5% hyperbaric bupivacaine in lower abdominal surgeries under spinal anaesthesia with primary objective as duration of analgesia and secondary objective as onset and two segment regression of sensory block, onset and duration of motor block, peri-operative sedation score, haemodyanamic changes, adverse effect if any.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-01-07
• Last Update Posted: 2020-06-24

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Patients belonging to ASA grade 1 and 2 Informed consent undergoing infraumbilical surgery.

Exclusion Criteria

Patient’s refusal Uncooperative patients Patient undergoing caesarean section Any known hypersensitivity or contraindication to Bupivacaine, Dexmedetomidine and Nalbuphine hydrochloride Local pathology at the site of injection or disability limiting the performance of spinal block History of convulsion, bleeding disorder, severe neurological deficit, thyroid disorder Patient with history of respiratory, cardiac, hepatic or renal disease (necessitating classification in ASA Class III or above) Patients having a history of significant neurological, psychiatric, or neuromuscular disorders.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of analgesia	1 year

Secondary Outcome Measures

Name	Time	Method
Onset and two segment regression of sensory block.	Onset and duration of motor block.

Trial Locations

Locations (1)

J L N Medical College and Hospital; 🇮🇳 Ajmer, RAJASTHAN, India

J L N Medical College and Hospital

🇮🇳Ajmer, RAJASTHAN, India

Dr Arvind Khare

Principal investigator

9414306114

arvindkhare68@gmail.com