Acute Myocardial Infarction From Clinical Presentation to Strategy Treatment
Overview
- Phase
- N/A
- Intervention
- Database
- Conditions
- Acute Coronary Syndrome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Enrollment
- 11000
- Locations
- 3
- Primary Endpoint
- Major Adverse Cardiac Events (MACEs)
- Status
- Recruiting
- Last Updated
- 3 months ago
Overview
Brief Summary
AMIPE is both a retrospective and prospective study which was designed in order to collect data of patients with acute coronary syndromes and myocardial injury and to improve the knowledge about these conditions.
Detailed Description
AMIPE is an observational, multicenter and both retrospective and prospective study enrolling a cohort of consecutive incident patients admitted to participating hospitals with a diagnosis of acute coronary syndrome or myocardial injury from 01/01/2016 to 31/12/2023. The aim of this study is to create a database including a comprehensive characterization of these patients in order to obtain new scientific evidence about these conditions. Informations about the patients will be gathered from in-hospital medical records. A written informed consent is needed for every prospective patients enrolled in the study, In particular, the main objectives of the study are: * document the characteristics of all patients presenting with acute coronary syndrome and myocardial injury; * document the long term outcome rates; * document the therapeutic regimens and investigation conformity of treatment with already established guidelines. Every diagnostic or therapeutic intervention will be in accordance with established guidelines and good clinical practice. Statistics will be conducted utilizing univariate and multivariate analysis for outcomes. In particular for what concerns univariate analysis, ordinal variables will be analysed with t-test and Mann-Whitney Test, whereas categorical responses with Fischer Exact Test and with Pearson Chi-square test. Multivariate analysis will be conducted with logistic regression for dichotomous variables, with mixed generalized linear model for ordinal or nominal variables and with ANOVA or MANOVA for continuous variables.
Investigators
Carmine Pizzi
Principal investigator
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Eligibility Criteria
Inclusion Criteria
- •Patient aged \> 18 years old
- •Acute coronary syndrome or myocardial injury
- •Written informed consent
Exclusion Criteria
- •under age or not able to give informed consent
Arms & Interventions
Patients with acute coronary syndrome or myocardial injury
Incident consecutive patients presenting with acute coronary syndrome or myocardial injury
Intervention: Database
Outcomes
Primary Outcomes
Major Adverse Cardiac Events (MACEs)
Time Frame: 5 years
MACEs rate
All cause mortality
Time Frame: 5 years
Death rate
All cause mortality
Time Frame: 1 year
Death rate
All cause mortality
Time Frame: 3 years
Death rate
Major Adverse Cardiac Events (MACEs)
Time Frame: 1 year
MACEs rate
Major Adverse Cardiac Events (MACEs)
Time Frame: 3 years
MACEs rate
Secondary Outcomes
- Differences in clinical presentation(5 year)
- Cardiovascular risk factors prevalence(5 year)
- Difference diagnosis between myocardial infarction subtypes and between myocardial infarction and myocardial injury(5 year)
- Differences and impact of periprocedural ischemic complications(5 year)
- Differences in flow characteristics(5 year)
- Cardiovascular risk factors prevalence(1 year)
- Cardiovascular risk factors prevalence(3 year)
- Differences in clinical presentation(3 year)
- Differences in clinical presentation(1 year)
- Differences in flow characteristics(1 year)
- Differences in flow characteristics(3 year)