The role of pregnancy on susceptibility and antibody dependent enhancement of immune cells for Zika virus infectio

Completed

• Conditions: Zika virus; 10047438; 10016849

• Registration Number: NL-OMON50935
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Pregnancy

Exclusion Criteria

Pregnancy complications

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main endpoints of this study are the ZIKV titers measured in the<br /><br>supernatant of infected PBMCs as well as the percentage of PBMCs that are<br /><br>infected with ZIKV.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary endpoints of this study are the cytokines detected in the<br /><br>supernatant of infected PBMCs from pregnant women and non pregnant women.</p><br>