Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic
试验速览
- 阶段
- 不适用
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- axial length measured by IOL-master
研究概览
简要总结
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
详细描述
1.The primary objective of the current study is to investigate changes in uncorrected visual acuity, diopter, accommodation, peripheral refraction, IOP, tear film quality, corneal thickness, corneal topography, corneal biomechanical parameters, objective optical quality, corneal and conjunctiva sensitivity and choroidal thickness for children with different diopters after wearing orthokeratology lenses; 2. Through measure long-term changes of these parameters, including corneal topography, axial length, peripheral refraction, objective optical quality and choroidal thickness, to explore occurrence and development regularity of myopia.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 8 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •subjects were 6-16 years of age; 2.had no other ocular diseases aside from refractive error and no keratoconus (confirmed by pre-treatment corneal topography);
- •had an intraocular pressure (IOP) of <21 mmHg;
- •had an with-the- rule astigmatism (axes 180 ± 30) ≤ 1.50 D; 5.had a best corrected visual acuity（BCVA） ≤0.00 log MAR units in both eyes (Snellen equivalent to 20/20);
排除标准
- •had binocular vision problems; 2.use medications that might affect refractive development; 3.had history of ortho-k or contact lens wear;
- •Ocular surface diseases and other eye diseases which can cause abnormalities of ocular surface;
- •Patients with histories of ocular injury or surgery;
- •Corneal staining and decentration of lens after wearing Ortho-k.
结局指标
主要结局
axial length measured by IOL-master
时间窗: 2 years
measured by IOL-master
次要结局
- corneal biomechanical parameters measured by Corvis-ST(2 years)
- corneal morphological characteristics measured by Optikon 2000 corneal topographer(2 years)
- IOP measured by Corvis-ST(2 years)
- tear film quality measured by Keratography(2 years)
- peripheral refraction measured by open field auto ref/keratometer measurements(WAM-5500,Grand Seiko)(2 years)
- corneal thickness measured by Corvis-ST(2 years)
- accommodation measured by open field auto ref/keratometer measurements(WAM-5500,Grand Seiko)(2 years)
- objective optical quality measured by OQAS visual quality analyzing system(2 years)
- corneal and conjunctiva sensitivity measured by Cochet-Bonnet(2 years)
- choroidal thickness measured by ocular coherence tomography(2 years)