A Study to Evaluate fMRI of Active DBS Stimulation in Epilepsy
Not Applicable
Withdrawn
- Conditions
- Refractory Epilepsy
- Registration Number
- NCT04753983
- Lead Sponsor
- Mayo Clinic
- Brief Summary
The purpose of this study is to use functional imaging to study the mechanisms of the anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS).
- Detailed Description
Researchers are testing how changing the settings on deep brain stimulation device (DBS) can help reduce the number and severity of seizures. Functional imaging will be used to study the mechanisms of ANT DBS to optimize the device settings to improve the degree of seizure reduction.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Patients who have previously undergone anterior thalamic nucleus deep brain stimulation (DBS) for refractory epilepsy.
Exclusion Criteria
- Contraindication to MRI; prior brain resective surgery or large area of brain tissue loss (e.g., large area infarction).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Document brain activation networks with ANT stimulation Results would be available immediately following processing of the imaging data after each scan Use resting state fMRI to map brain network activation with high and low frequency of ANT stimulation.
- Secondary Outcome Measures
Name Time Method