MedPath

Binafuxi granule in the treatment of common cold (heat syndrome): a phase III clinical trial

Phase 3
Conditions
Common cold with heat syndrome
Registration Number
ITMCTR2100005376
Lead Sponsor
West China Hospital, Sichuan University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Male
Target Recruitment
Not specified
Inclusion Criteria

(1) Diagnosis of common cold according to Western medicine and symptom presenting within 48 hours;
(2) With fever and body temperature between 37.5 degree Celsius and 39 degrees Celsius;
(3) Diagnosis of common cold with heat syndrome according to traditional Uighur medicine;
(4) Aged between 18 and 65 years;
(5) Willing to participate and sign the informed consent.

Exclusion Criteria

(1) Diagnosis of common cold with cold syndrome according to traditional Uighur medicine;
(2) Patients with influenza, acute or chronic rhinitis, acutel sinusitis, suppurative tonsillitis, pneumonia and Tuberculosis;
(3) white blood cell count>11.0 × 10^9/L and/or neutrophils percentae > 80%;
(4) Patients who are taking any medication to treat common cold;
(5) Patients with gastrointestinal discomfort symptoms such as acute and chronic diarrhea;
(6) Patients with serious primary diseases of the cardiovascular, pulmonary, kidney, liver, neurological and hematological system;
(7) Pregnant women, lactating women, or women who have a birth plan;
(8) Patients with allergic constitution or being allergic to the study drug;
(9) Patients who are participating in or have participated in another drug clinical trial within the last 3 months;
(10) Patients who have been judged by the investigator as inappropriate to participate in the clinical trial.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The disappearance rate of all symptoms after taking medicine for 3 days;
Secondary Outcome Measures
NameTimeMethod
Rate of body temperature returned to normal after taking medicine for 1 day, 2 days, 3 days;Time to fever relief;Usage of emergency drug;Time to fever clearance;Traditional Uyghur medicine symptom score;Rate of single symptom disappeared after taking medicine for 1 day, 2 days, 3 days;The duration of all symptoms;
© Copyright 2025. All Rights Reserved by MedPath