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Clinical evaluation of the efficacy of purified bioactive peptides from Spirulina Platensis algae on the healing of wounds after periodontal flap surgery (double-blinded randomized clinical trial)

Phase 1
Recruiting
Conditions
Wounded tissue caused by periodontal flap surgery.
Disruption of wound, not elsewhere classified
T81.3
Registration Number
IRCT20221021056257N1
Lead Sponsor
Tabriz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

Having a favorable general health condition
Being available during the 12 weeks of study
Non- smoker patients
Diagnosis of periodontitis, as defined by at least three non-contiguous interproximal pockets with pocket depth (PPDs) greater than 4mm or other radiographic evidence such as alveolar bone loss
Patients who show PPD = 6mm after non-surgical treatment and periodontal surgery is indicated.

Exclusion Criteria

Pregnant women
People who had used antibiotics and anti-inflammatory drugs within a month before surgery
Patients who use orthodontic appliances
Patients using the removable prosthesis
Patients with intraoral pathological conditions
Patients with 5 or more decayed teeth
Patients who had participated in another study during the last 1 month
Patients with a history of allergic reaction to health care products
Patients who are forbidden to eat or drink liquids for 4 hours due to medical conditions

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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