Implementation and Evaluation of "Mindfulness-Based Cognitive Therapy" in a Health Care Region in Flanders: a Randomized Clinical Trial
Not Applicable
Completed
- Conditions
- Recurrent Depression
- Registration Number
- NCT00259506
- Lead Sponsor
- University Hospital, Ghent
- Brief Summary
Research project regarding the possibility to implement and the efficacy of a non-drug, psychotherapeutic intervention (MBCT), in preventing relapse/recurrence of depression.
- Detailed Description
This trial is based on the following publications:
Teasdale JD, Segal ZV, Williams JMG, Ridgeway VA, Soulsby JM, Lau MA. Prevention of relapse / recurrence in major depression by Mindfulness-Based Cognitive Therapy. Journal of Consulting and Clinical Psychology 2000; 68(4): 615-623.
Ma SH, Teasdale JD. Mindfulness-Based Cognitive Therapy for depression: replication and exploration of differential relapse prevention effects. Journal of Consulting and Clinical Psychology 2004; 72(1): 31-40.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 405
Inclusion Criteria
- Age: 18 years and above
- place of residence in accordance with a well-defined region (pilot study)
- given informed consent
- diagnosis of recurrent depression (DSM-IV-TR)
- at least 3 depressive episodes in the anamnesis (depression: either primary or secondary diagnosis)
- last depressive episode at least 8 weeks ago (DSM-IV-TR)
- absence of a present depressive episode
- history of treatment by an antidepressant medication
- HRSD-score <14 at baseline assessment (Hamilton Rating Scale for Depression, HRSD-17)
- absence of exclusion criteria
Exclusion Criteria
- based on DSM-IV-TR: current diagnosis of any of the following psychiatric disorders: lifetime mood disorder, chronic depression, dysthymia, current substance abuse, obsessive-compulsive disorder, bipolar disorder, acute psychosis, cognitive disorder, organic mental disorder, pervasive developmental disorder, mental retardation, primary diagnosis of axis-II-disorder, at risk for suicide
- Extended experience with zen- or vipassana meditation (or mindfulness) in the past or
- more than 1 hour practice of zen- or vipassana meditation (or mindfulness) per week during the last 8 weeks
- other meditation practices except for MBCT during the training
- more than 1 psychiatric consultation per 3-4 weeks during the training and follow-up
- intensive psychotherapy during the training and follow-up
- schizophrenia or schizoaffective disorder in the anamnesis
- physical problems which make it difficult to participate in the programme
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Feasibility to implement MBCT in a Flemish region Relapse/recurrence of depression after approximately 12 months
- Secondary Outcome Measures
Name Time Method Health status Quality of life Coping Fear Rumination
Trial Locations
- Locations (1)
University Hospital Ghent
🇧🇪Ghent, Belgium