Developing and evaluating a mobile phone-based early alert system using high-resolution air quality forecast to improve asthma control in Malaysia

Not Applicable

Active, not recruiting

• Conditions: Improving asthma control among adult patients with asthma during increased outdoor pollution.; Respiratory

• Registration Number: ISRCTN14489433
• Lead Sponsor: Accord (United Kingdom)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-01
• Last Update Posted: 21 August 2023
• Study Completion: 2025-06-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Adult patients aged 18 years old and above with physician-diagnosed asthma and receiving asthma treatment in the previous year
2. Adult patients who live in Klang District for the duration of the study
3. Patients who had reported poor asthma control and exacerbation aggravated by haze (findings from baseline study in RESPIRE 1)
4. Patients who are on controller medication (e.g., an inhaled corticosteroid (ICS), inhaled combination ICS/long-acting beta-agonists (LABA), leukotriene receptor antagonist (LTRA))
5. Patients who own and are able to use a smartphone
6. Patients who are able to understand the Malay/English language
7. Patients who are willing and able to give consent to participate in the study

Exclusion Criteria

1. Patients below 18 years of age
2. Patients who have respiratory symptoms (e.g., cough, breathlessness, wheezing) due to other conditions for example established physician diagnoses of:
2.1. Respiratory infection e.g., pneumonia, tuberculosis (but not having underlying asthma)
2.2. Chronic obstructive pulmonary diseases
2.3. Congenital heart disease
2.4. Heart, liver or renal failure
2.5. Gastro-esophageal reflux
2.6. Active life-threatening malignancy and those receiving palliative care
3. Patients who have disabilities (physical/psychological) that may interfere with the completion of the study
4. Patients who are unwilling or unable to provide written informed consent (e.g. cognitive impairment)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Asthma control measured using the Global Initiative for Asthma (GINA) Asthma Symptoms Control scoring at 1, 3, 6 and 12 months