Levosimendan Versus Dobutamine in Cardiopatic Patients Undergoing Major Non Cardiac Surgery

Phase 4

• Conditions: Cardiovascular Diseases
• Interventions: Drug: Dobutamine; Drug: Levosimendan

• Registration Number: NCT02012946
• Lead Sponsor: Azienda Policlinico Umberto I

Brief Summary

This study wants to investigate the hemodynamic changes in cardiopatic patients undergoing major non cardiac surgery, during and after the continuous infusion of levosimendan or dobutamine.

Detailed Description

Not available

Study Timeline

• Status Verified: 2013-12
• Study Start: 2013-12
• Primary Completion: 2013-12
• Study First Submitted: 2013-12-11
• Study First Submitted QC: 2013-12-11
• Last Update Submitted: 2013-12-11
• Study First Posted: 2013-12-17
• Last Update Posted: 2013-12-17

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• EF < 40%, no liver and renal disfynction, chronic cardiopathy

Exclusion Criteria

• acute coronary syndrome, life expectation <30 days, hemodialysis, ventricular tachycardia/ventricular fibrillation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
dobutamine	Dobutamine	patient receiving dobutamine
Levosimendan	Levosimendan	patient receiving levosimendan

Primary Outcome Measures

Name	Time	Method
cardiac index	1-3 days

Trial Locations

Locations (1)

Francesco Pugliese; 🇮🇹 Rome, Italy