NCT02012946UnknownPhase 4
Levosimendan Versus Dobutamine in Cardiopatic Patients Undergoing Major Non Cardiac Surgery
Azienda Policlinico Umberto I1 site in 1 country40 target enrollmentStarted: December 2013Last updated:
Conditions
Interventions
Drugs
Trial Snapshot
- Phase
- Phase 4
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- cardiac index
Study Overview
Brief Summary
This study wants to investigate the hemodynamic changes in cardiopatic patients undergoing major non cardiac surgery, during and after the continuous infusion of levosimendan or dobutamine.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Supportive Care
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 85 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •EF < 40%, no liver and renal disfynction, chronic cardiopathy
Exclusion Criteria
- •acute coronary syndrome, life expectation <30 days, hemodialysis, ventricular tachycardia/ventricular fibrillation
Arms & Interventions
dobutamine
Active Comparator
patient receiving dobutamine
Intervention: Dobutamine (Drug)
Levosimendan
Active Comparator
patient receiving levosimendan
Intervention: Levosimendan (Drug)
Outcomes
Primary Outcomes
cardiac index
Time Frame: 1-3 days
Secondary Outcomes
No secondary outcomes reported
Investigators
francesco pugliese
professor
Azienda Policlinico Umberto I
Study Sites (1)
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