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Clinical Trials/NCT04385355
NCT04385355
Recruiting
Not Applicable

Influence of the Design of the Transmucosal Abutment on the Marginal Periimplant Bone Loss. Randomized Clinical Trial

University of Santiago de Compostela1 site in 1 country36 target enrollmentOctober 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Peri-implant Marginal Bone Loss
Sponsor
University of Santiago de Compostela
Enrollment
36
Locations
1
Primary Endpoint
Radiographic marginal periimplant bone level changes
Status
Recruiting
Last Updated
4 years ago

Overview

Brief Summary

The objective of this study is to evaluate the radiographic changes on the marginal peri-implant bone level on bone level implants with a narrower transmucosal abutment, in comparison to the conventional abutment, both of 3mm height

Detailed Description

Patients will receive from one to eight bone-level implants according to their rehabilitation necessity and transmucosal abutments will be connected the day of the surgery. The control group will receive conventional transmucosal abutments while the test group will receive TCP abutments, with a narrower design. Results will be evaluated initially 6 and 12 months after the connection of the definitive prostheses, and finally 3 years later.

Registry
clinicaltrials.gov
Start Date
October 1, 2024
End Date
November 1, 2024
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Juan Blanco Carrión

Professor

University of Santiago de Compostela

Eligibility Criteria

Inclusion Criteria

  • Absence of systemic and periodontal pathology, over 18 years of age, with a plaque index below 25%.
  • Absence of at least one tooth, with natural adjacent teeth, allowing a prosthetic rehabilitation with an osseointegrated implant and a prosthetic unit.
  • Adequate bone quality available, allowing placement of MOZO GRAU® implants InHex STD QUATTRO with diameters of 3.75 mm or 4.25 mm and lengths of 8, 10 and 11.5 mm.
  • Natural teeth or implants with fixed restoration as antagonists.

Exclusion Criteria

  • Systemic factors:
  • Continuous administration of systemic medication that can interfere with the bone metabolism or medical conditions requiring prolonged use of steroids and / or medications that can interfere with bone metabolism.
  • History of leukocyte dysfunction and deficiency, immunodeficiency syndromes, kidney failure or bone metabolic disorders, such as osteoporosis.
  • Physical disability that may interfere with proper oral hygiene.
  • Use of any investigational medication or device within the previous 30 days to implant surgery in the study.
  • Alcoholism or drug addiction
  • Smoker of more than 10 cigarettes per day.
  • Conditions or circumstances that could prevent compliance with participation in study or interfere with the analysis of results, such as a history of breach or unreliability.
  • Local factors:
  • History of local radiotherapy.

Outcomes

Primary Outcomes

Radiographic marginal periimplant bone level changes

Time Frame: from baseline (connection of the definitive abutment) to 6 and 12 months after the definitive prostheses will be connected, and finally 3 years later

Measured as the distance from the bone crest to the first implant-to-bone contact. This will be assessed on parallelized periapical radiographies

Secondary Outcomes

  • Bleeding on probing(6 and 12 months after the definitive prostheses will be connected, and finally 3 years later)
  • Probing pocket depth(6 and 12 months after the definitive prostheses will be connected, and finally 3 years later)
  • Papilla refill(6 and 12 months after the definitive prostheses will be connected, and finally 3 years later)
  • Patient Reported Outcomes Measurements(6 and 12 months after the definitive prostheses will be connected, and finally 3 years later)
  • Plaque index(6 and 12 months after the definitive prostheses will be connected, and finally 3 years later)
  • Adverse effects frequency(6 and 12 months after the definitive prostheses will be connected, and finally 3 years later)

Study Sites (1)

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