ARC in Hemorrhagic Stroke
Completed
- Conditions
- Hemorrhagic StrokeAugmented Renal Clearance
- Interventions
- Other: No intervention
- Registration Number
- NCT02386202
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Brief Summary
To determine the incidence and predictors of augmented renal clearance (ARC) in patients with hemorrhagic stroke.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
- Adults ≥ 18 years
- Patients with hemorrhagic stroke
- Anticipated length of stay in the neuroscience intensive care unit > 48 hours
- Informed consent provided by the patient or by the patient's designated medical proxy
Exclusion Criteria
- Pregnancy
- Patients with pre-existing renal dysfunction (chronic kidney disease stages 3 - 5)
- Patients receiving renal replacement therapy
- Patients with an admission serum creatinine > 1.4 mg/dL
- Patients with non-aneurysmal subarachnoid hemorrhage
- Patients with history of nephrectomy or body mass index < 18 kg/m2
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients with hemorrhagic stroke No intervention All patients with hemorrhagic stroke admitted to the neurosciences ICU are eligible for study enrollment.
- Primary Outcome Measures
Name Time Method To describe the onset, magnitude, and change over time of ARC in patients with hemorrhagic stroke Over neurosciences intensive care unit stay Daily 8-hour urine collections will be performed to directly measure creatinine clearance up to ICU discharge
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of North Carolina Hospitals
🇺🇸Chapel Hill, North Carolina, United States