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临床试验/NCT02386202
NCT02386202已完成不适用

Augmented Renal Clearance in Hemorrhagic Stroke Patients Admitted to the Neurosciences Intensive Care Unit

University of North Carolina, Chapel Hill1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2015年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
80
试验地点
1
主要终点
To describe the onset, magnitude, and change over time of ARC in patients with hemorrhagic stroke

研究概览

简要总结

To determine the incidence and predictors of augmented renal clearance (ARC) in patients with hemorrhagic stroke.

研究设计

研究类型
Observational
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults ≥ 18 years
  • Patients with hemorrhagic stroke
  • Anticipated length of stay in the neuroscience intensive care unit > 48 hours
  • Informed consent provided by the patient or by the patient's designated medical proxy

排除标准

  • Pregnancy
  • Patients with pre-existing renal dysfunction (chronic kidney disease stages 3 - 5)
  • Patients receiving renal replacement therapy
  • Patients with an admission serum creatinine > 1.4 mg/dL
  • Patients with non-aneurysmal subarachnoid hemorrhage
  • Patients with history of nephrectomy or body mass index < 18 kg/m2

结局指标

主要结局

To describe the onset, magnitude, and change over time of ARC in patients with hemorrhagic stroke

时间窗: Over neurosciences intensive care unit stay

Daily 8-hour urine collections will be performed to directly measure creatinine clearance up to ICU discharge

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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ARC in Hemorrhagic Stroke | 临床试验