ARC in Hemorrhagic Stroke

Completed

• Conditions: Hemorrhagic Stroke; Augmented Renal Clearance

• Registration Number: NCT02386202
• Lead Sponsor: University of North Carolina, Chapel Hill

Brief Summary

To determine the incidence and predictors of augmented renal clearance (ARC) in patients with hemorrhagic stroke.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2015-03-05
• Study First Submitted QC: 2015-03-10
• Study First Posted: 2015-03-11
• Primary Completion: 2015-08
• Study Completion: 2015-08
• Status Verified: 2015-12
• Last Update Submitted: 2015-12-01
• Last Update Posted: 2015-12-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Adults ≥ 18 years
• Patients with hemorrhagic stroke
• Anticipated length of stay in the neuroscience intensive care unit > 48 hours
• Informed consent provided by the patient or by the patient's designated medical proxy

Exclusion Criteria

• Pregnancy
• Patients with pre-existing renal dysfunction (chronic kidney disease stages 3 - 5)
• Patients receiving renal replacement therapy
• Patients with an admission serum creatinine > 1.4 mg/dL
• Patients with non-aneurysmal subarachnoid hemorrhage
• Patients with history of nephrectomy or body mass index < 18 kg/m2

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To describe the onset, magnitude, and change over time of ARC in patients with hemorrhagic stroke	Over neurosciences intensive care unit stay	Daily 8-hour urine collections will be performed to directly measure creatinine clearance up to ICU discharge

Trial Locations

Locations (1)

University of North Carolina Hospitals; 🇺🇸 Chapel Hill, North Carolina, United States