Induced hypertension for delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage: a feasibility study - Induced hypertension for DCI after SAH

niversitair Medisch Centrum Utrecht0 个研究点目标入组 24 人开始时间: 待定最近更新: 2024年5月13日

适应症

试验速览

暂无简介。

•1. Admission to the hospital
•2. Age 18 years or over
•3. Aneurysmal SAH, demonstrated on CT-angiography or cerebral agiograph, with onset less than 72 hours before admission
•4. Glascow Coma Sum Score above 8.
•5. DCI (decrease of 2 GSC points or all new neurological focal deficits), diagnosed by a neurologist, neurosurgeon or intensivist within 3 hours after deterioration.
•6. Informed consent

•1. Symptomatic cerebral aneurysm not yet treated by coiling or clipping
•2. Co-existing severe head injury.
•3. A history of a cardiac rhythm disorder, necessitating medical treatment.
•4. A history of a left ventricular pump failure, necessitating medical treatment.
•5. Pregnancy.
•6. Known allergy for CT-contrast agents.
•7. Renal failure, defined as a serum creatinine > 150 µmol/l
•8. Other causes cause for neurological deterioration (see page 15 of the study protocol for the differential diagnosis)
•9. Severe hypertension, defined as a MAP of 120 mmHg or higher

发起方

niversitair Medisch Centrum Utrecht