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临床试验/NCT01935895
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Combined Exercise Circuit Session Acutely Attenuates Stress-Induced Blood Pressure Reactivity in Healthy Adults

Universidade Federal do vale do São Francisco1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2010年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
1
主要终点
Combined Exercise Circuit Session Acutely Attenuates Stress-Induced Blood Pressure Reactivity in Healthy Adults

研究概览

简要总结

Introduction: Daily stress levels of population are increasing over the last decades. Frequent spouse to stress is considered an important risk factor for development of cardiovascular diseases. Other well documented risk factor for cardiovascular diseases is systemic hypertension which, in turn, has been related to elevated blood pressure reactivity (BPR) to stress. The exacerbated BPR may suggest a poor autonomic modulation due to an elevated sympathetic tone, condition that has been associated with medium to long-term cardiovascular complications. Also, some reports have demonstrated that individuals hyper-reactive to stress chronically increase their risk for psychological disorders such as anxiety, irritability and frustration. These feelings are associated to increased sympathetic tone induced chronic elevation in BP. Although the hemodynamic benefits of aerobic and resistance exercises had been documented in a variety of reports5, the acute effects of the aforementioned exercise modes combined in a circuit method on post-exercise BP, including the responses to cardiovascular stressor test need further investigations. Objective: To investigate the blood pressure (BP) responses to cardiovascular stressor test after a combined exercise circuit session at moderate intensity. Methods: Twenty individuals (10male/10fem; 33.4±6.9years; 70.2±15.8kg; 170.4±11.5cm; 22.3±6.8 %body fat) volunteered to randomly perform on different days: 1) Exercise session consisting of 3-laps in a circuit model in the following sequence: knee extension, bench press, knee flexion, rowing in the prone, squat, shoulder press and 5-min of aerobic exercise at 75-85% of age-predicted maximum heart rate and/or 13 in the Borg-Scale [6-20]. The sets of resistance exercise were composed by 15 repetitions with ~50% of one repetition maximum test and; 2) a control session without exercise. The systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured at resting and during 1h of recovery in both experimental sessions. After that, blood pressure reactivity (BPR) was evaluated using the Cold Pressor Test (a test with hand in the cold water during one minute). The hypotheses are that after doing the exercise session occur attenuation of blood pressure increase during the Cold Pressor Test compared to sitting without exercise (control session).

详细描述

* Subjects:

  • Twenty apparently healthy individuals of both genders (10 men and 10 women) with a mean age of 33.4±6.9 years (24 - 50 years), weight of 70.2±15.8 kg (45 - 96 kg), height of 170.4±11.5 cm (149 - 192 cm), body mass index (BMI) of 23.9±3.5 kg/m2(-1) (19.2 - 23.7 kg/m2(-1)) and percent body fat of 22.3±6.8% (8.5 - 35.0 %) volunteered for participation. The classification of the subjects in "apparently healthy" was performed by the risk stratification criteria of the American College of Sports Medicine in 1995 (interview with signs, symptoms and/or cardiopulmonary risk factors). No subject was using any medication and had no history of diagnosed cardiovascular or metabolic disease.

The study was conducted in accordance to the Declaration of Helsinki and was approved by the Institutional Committe (CEDEP - COMITÊ DE ÉTICA E DEONTOLOGIA EM ESTUDOS E PESQUISAS), Petrolina-PE (protocol 0047.0.441.000-10). All participants were informed on the experimental methods before giving written consent.

  • Anthropometric Assessment:
  • Standard procedures were used to measure weight, height and body mass index (BMI). Body density was determined with specifications by Jackson & Pollock16 for men ([1,1093800 - 0,0008267 * (sum of skinfolds of the chest, abdomen and thigh) + 0,0000016 * (sum of skinfolds of the chest, abdomen and thigh)2 - 0,0002574 * age]) and Jackson et al.17 for women ([1,0994921 - 0,0009929 * (sum of skinfolds of the triceps, suprailiac and thigh) + 0,0000023 * (sum of skinfolds of the triceps, suprailiac and thigh)2 - 0,0001392 * age]). Body fat percentage was derived from Siri equation ([4.91 / density - 4.5] * 100).
  • Blood Pressure Measurement:

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
24 Years 至 50 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Apparently healthy individuals
  • between 24 and 50 years

排除标准

  • Using any medication
  • History of diagnosed cardiovascular or metabolic disease

结局指标

主要结局

Combined Exercise Circuit Session Acutely Attenuates Stress-Induced Blood Pressure Reactivity in Healthy Adults

时间窗: 4 months

次要结局

  • Combined Exercise Circuit Session Acutely Attenuates Stress-Induced Blood Pressure Reactivity in Healthy Adults(4 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sérgio Rodrigues Moreira

Research professor of the College of Physical Education

Universidade Federal do vale do São Francisco

研究点 (1)

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