Efficient Postoperative Pain Management With Multimodal IV

Not Applicable

Completed

• Conditions: Post Operative Pain
• Interventions: Drug: Multimodal IV analgesia; Drug: epidural analgesia

• Registration Number: NCT06661746
• Lead Sponsor: Benha University

Brief Summary

Postoperative pain remains a prevalent concern despite ongoing improvements in surgical methods and pain management strategies. Opioids, while commonly prescribed, frequently lead to undesirable side effects. Epidural analgesia, though a viable option, carries its risks and complications. Recent research indicates that combining intravenous lidocaine and ketamine can significantly alleviate postoperative pain and decrease the reliance on opioids within the initial 24 hours following surgery. This approach offers a promising alternative with minimal additional adverse effects, suggesting a potential shift in pain management practices.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-07-15
• Study First Submitted: 2024-10-25
• Study First Submitted QC: 2024-10-25
• Study First Posted: 2024-10-28
• Primary Completion: 2024-10-30
• Study Completion: 2024-11-15
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-19
• Last Update Posted: 2024-12-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients were assigned for surgical intervention;
• Patients of ASA grade I-III;
• Patients were free of exclusion criteria;

Exclusion Criteria

• Patients who are not in ASA grade I-III;
• Patients who had uncontrolled hypertension and/or diabetes mellitus;
• Patients who had uncompensated cardiac, renal, or hepatic diseases;
• Patients with coagulopathy, spinal deformity, allergy, or contraindication for the used drugs;
• Patients who refused to sign the informed consent were excluded from the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Multimodal Group	Multimodal IV analgesia	-
Epidural Group	epidural analgesia	-

Primary Outcome Measures

Name	Time	Method
Proportion of patients reporting at least a 50% reduction in pain (measured by Numerical Rating Scale) in post-Operative follow up.	3 months	Value of Multimodal injection in Pain Reduction post operatively manifested by recurrence of pain.

Trial Locations

Locations (1)

Benha University; 🇪🇬 Banhā, El Qalyoubia, Egypt