Photoacoustic Tomography (PAT) in combination with high resolution ultrasound evaluating non-invasive diagnostic parameters of diabetic microangiopathy

• Conditions: E10; E11; Type 1 diabetes mellitus; Type 2 diabetes mellitus

• Registration Number: DRKS00008563
• Lead Sponsor: Klinik für Dermatologie, Venerologie und AllergologieUniversitätsklinikum Essen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-05-26
• Study Completion: 2016-04-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

100 patients with insulin-dependent diabetes mellitus or non-insulin-dependent diabetes mellitus under ongoing pharmaceutical therapy;
100 patients without diabetes mellitus (control cohort)

Exclusion Criteria

Age < 18 years,
Intolerance of ultrasound gel,
Known peripheral small vessel disease if patient is screened as non-diabetic,
Persistent ulcers in measurement area,
Moderate or severe peripheral vascular disease

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
hemoglobin concentration (oxygenated) in a 3D image of the ventral trunk, the hands and the feet

Secondary Outcome Measures

Name	Time	Method
change in blood vessel diameter before and after an occlusion of the blood flow