Multispectral Photoacustic Tomography (MSOT) as a new diagnostic tool for Psoriatic Arthritis (PsA)

Not Applicable

• Conditions: L40.5; L40.0; Arthropathic psoriasis; Psoriasis vulgaris

• Registration Number: DRKS00021183
• Lead Sponsor: niversitätsklinikum Essen (AöR)Allgemeine Poliklinik, PsoriasisKlinik für Dermatologie, Venerologie und Allergologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-03-26
• Study Completion: 2023-09-14
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting stopped after recruiting started
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

40 patients with psoriasis and pain and/or swelling and/or movement restrictions in the finger joints
- 40 healthy volunteers without psoriasis/ psoriatic arthritis

Exclusion Criteria

- Age < 18 years
- Insufficient communication skills in the German language or lack of understanding of the German language
- (Functional) Illiteracy
- Lack or absence of the patient's ability to consent

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Read-out parameter of this study should be the rate of MSOT findings positive for PsA compared to the diagnosis of a rheumatologist.

Secondary Outcome Measures

Name	Time	Method
- Sum of pixels in the region of interest (ROI) of the signals of oxygenated and deoxygenated hemoglobin <br><br>- Blood flow intensity as measured with the quantified amount of the optoacoustic signal.